Pyknons of Dr. Rigoutsos and FractoGene
*NEW*
Pellionisz, A. (15 May, 2006, submitted to IPGS European Inaugural)
POSTGENETICS: GENETICS BEYOND GENES.
THE JOURNEY OF DISCOVERY OF THE FUNCTION OF “JUNK DNA”
FractoGene finds objects, named
each FractoSet containing iterative Pyknon-type sequences
as a material base for reverberative synthesis of protein structures
Breakthrough discovery of Rigoutsos et al. (2006) of self-similar, repetitive elements (what they call "Pyknons") throughout the coding- as well as non-coding "Junk" DNA may raise the question how the novel findings relate to fractality of the DNA. (This FractoGene work is already in progress, with astounding preliminary results regarding pyknon-patterns found in other than human DNA, of a cardinally important species). The FractoGene concept in PostGenetics interprets protein synthesis as an iterative process, based on recursion to DNA, which constitutes "fractal sets" - in a causal relationship to the emerging organismal hierarchies that DNA determines.
Pyknons
Some visual relationship can immediately be drawn between the new findings and the the FractoGene concept:
Pyknons by Dr. Rigoutsos et al., 2006 (Their Fig.1.)
Pyknons and FractoGene
Below, Fig. 1. by Dr. Rigoutsos (et al, 2006) is highligted (in black) by AJP:
Possibility for a hierarchical, recursive access to "Pyknon-sets" with an accumulating number of elements: 2-component pyknon sequence in 11 instances in (A), 3-component pyknons in 4 instances in (B) and 4-component pyknons in 2 instances in (C):
A.
B.
C.
Another, diverging venue for a hierarchical, recursive access to 4-element pyknon-sets; 11 instances of 2-element pyknons sets (D, identical to A above), 4 instances of 3-element pyknon sets (E, identical to B above) and 2 *different* instances of 4-element pyknon sets (F, the two instances of 4-element pyknon-sets are *different* from the above C):
D.
E.
F.
The conceptual interpretation of "self-similar repetitive elements as fractal sets" in DNA were depicted (2002) in FractoGene (note that diagram of 2002 was for visualization purposes only - state of art of FractoGene is much advanced since): See general information on "Junk DNA".

FractoGene did provide not only a functional interpretation of self-similar repetitive sequences of DNA, but also came forward with experimentally falsifiable or verifiable quantitative predictions. The "Fugu prediction" has already received experimental support, now published. The "Methylation prediction" (for silencing "PostGenes", amenable as a method for "PostGene Discovery") is presently tested. FractoGene, within 72 hours of appearance of the "pyknons" results of Dr. Rigoutsos (et al, 2006), is ready with 3 novel, experimentally verifiable or falsifiable predictions. (Parties interested in experimental tests may contact pellionisz_at_junkdna.com).
FractoGene project is in progress, with astounding preliminary results regarding fractal interpretation of pyknon-patterns in a most important non-human DNA.